Children's Health and Wellness

Imipenem, Cilastatin Sodium Suspension for injection

What is this medicine?

IMIPENEM; CILASTATIN (i mi PEN em; sye la STAT in) is a carbapenem antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

How should I use this medicine?

This medicine is infused into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborn for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in blood pressure

  • change in hearing

  • confusion

  • dark urine

  • dizziness

  • fast, irregular heartbeat

  • fever

  • general ill feeling or flu-like symptoms

  • light-colored stools

  • loss of appetite, nausea

  • muscle stiffness or twitch

  • pain at site where injected

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • right upper belly pain

  • seizures

  • trouble passing urine or change in the amount of urine

  • unusually weak or tired

  • vomiting

  • yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • headache

  • stomach upset or pain

  • too much saliva in the mouth

What may interact with this medicine?

  • ganciclovir

  • probenecid

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

You will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • brain tumor or lesion

  • kidney disease

  • seizure disorder

  • an unusual or allergic reaction to imipenem, cilastatin, other antibiotics or medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better, if they get worse, or if you get new symptoms. Your doctor will monitor your condition and blood work as needed.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

Date Last Reviewed:
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