Children's Health and Wellness

Tobramycin Sulfate Nebulizer solution

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat or prevent certain kinds of bacterial infections in the lungs. It will not work for colds, flu, or other viral infections.

How should I use this medicine?

This medicine is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. You will be taught how to use your nebulizer. Follow the directions on your prescription label. Do not use more often than directed.

You will get an information sheet with each prescription and refill. Read this sheet carefully each time. This sheet may change.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • change in amount or color of urine

  • change in hearing

  • dizziness

  • fever or infection

  • loss of balance

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • unusual bleeding or bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • changes in voice

  • cough

  • headache

  • nausea, vomiting

  • runny nose

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cidofovir

  • cisplatin

  • colistin

  • ethacrynic acid

  • furosemide

  • mannitol

  • other aminoglycoside antibiotics

  • polymyxin

  • urea

  • vancomycin

  • viomycin

This medicine may also interact with the following medications:

  • diuretics

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Take your doses at least 6 hours apart. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). You can also store this medicine at room temperature, up to 25 degrees C (77 degrees F) and throw away any unused medicine after 28 days. Protect from light. Do not use if the medicine is cloudy. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • balance problems

  • hearing problems

  • kidney disease

  • myasthenia gravis

  • Parkinson's disease

  • an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional as directed. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Date Last Reviewed:
© 2000-2014 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.